CD3D, GZMK, and KLRB1 Are Potential Markers for Early Diagnosis of Rheumatoid Arthritis, Especially in Anti-Citrullinated Protein Antibody-Negative Patients

• Главные авторы: Junqin Lu (Автор), Yihui Bi (Автор), Yapeng Zhu (Автор), Shi Huipeng (Автор), Wenxiu Duan (Автор), Jian Zhou (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Предметы: article
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Early diagnosis and monitoring of rheumatoid arthritis (RA) progress are critical for effective treatment. In clinic, the detection of rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) are usually combined to diagnose early RA. However, the poor specificity of RF and high heter...