Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure.

• Main Authors: Amanda Fortes Francisco (Author), Ursula Saade (Author), Shiromani Jayawardhana (Author), Hans Pottel (Author), Ivan Scandale (Author), Eric Chatelain (Author), Peter Liehl (Author), John M Kelly (Author), Maan Zrein (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is a serious public health problem throughout Latin America. With 6 million people infected, there is a major international effort to develop new drugs. In the chronic phase of the disease, the pa...