Free interstitial levels of metformin in the liver of healthy and diabetic Wistar rats

Abstract In the present study, free interstitial levels reached by metformin in the liver were investigated in control and diabetic rats by microdialysis. Firstly, a bioanalytical method using an HPLC-UV system to determine the drug concentration in microdialysis samples was validated. The blood glu...

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Main Authors: Andressa Braga (Author), Jaqueline Schneider Izolan (Author), Teresa Cristina Dalla Costa (Author), Bibiana Verlindo de Araújo (Author)
Format: Book
Published: Universidade de São Paulo, 2022-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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