Free interstitial levels of metformin in the liver of healthy and diabetic Wistar rats
Abstract In the present study, free interstitial levels reached by metformin in the liver were investigated in control and diabetic rats by microdialysis. Firstly, a bioanalytical method using an HPLC-UV system to determine the drug concentration in microdialysis samples was validated. The blood glu...
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Format: | Book |
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Universidade de São Paulo,
2022-06-01T00:00:00Z.
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A1234.567 |
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