Effects of aerobic and inspiratory training on skeletal muscle microRNA‐1 and downstream‐associated pathways in patients with heart failure

• Main Authors: Ligia M. Antunes‐Correa (Author), Patricia F. Trevizan (Author), Aline V.N. Bacurau (Author), Larissa Ferreira‐Santos (Author), João L.P. Gomes (Author), Ursula Urias (Author), Patricia A. Oliveira (Author), Maria Janieire N.N. Alves (Author), Dirceu R. deAlmeida (Author), Patricia C. Brum (Author), Edilamar M. Oliveira (Author), Ludhmila Hajjar (Author), Roberto Kalil Filho (Author), Carlos Eduardo Negrão (Author)
• Format: Book
• Published: Wiley, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The exercise intolerance in chronic heart failure with reduced ejection fraction (HFrEF) is mostly attributed to alterations in skeletal muscle. However, the mechanisms underlying the skeletal myopathy in patients with HFrEF are not completely understood. We hypothesized that (i)...