Development and Validation of a Simple UV-HPLC Method to Quantify the Memantine Drug Used in Alzheimer's Treatment

• Главные авторы: Débora Nunes (Автор), Tânia G. Tavares (Автор), Frenacisco Xavier Malcata (Автор), Joana A. Loureiro (Автор), Maria Carmo Pereira (Автор)
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• Опубликовано: MDPI AG, 2024-09-01T00:00:00Z.
• Предметы: article
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Memantine, a non-competitive NMDA receptor antagonist, is used to treat Alzheimer's disease. Therefore, loading memantine in nanoparticles (NPs) could be an essential tool to improve the treatment effectiveness while reducing drug toxicity. Even though some approaches have been described to qua...