FMRFamide-like peptides (FLPs) enhance voltage-gated calcium currents to elicit muscle contraction in the human parasite Schistosoma mansoni.

• Main Authors: Ekaterina Novozhilova (Author), Michael J Kimber (Author), Hai Qian (Author), Paul McVeigh (Author), Alan P Robertson (Author), Mostafa Zamanian (Author), Aaron G Maule (Author), Tim A Day (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomes are amongst the most important and neglected pathogens in the world, and schistosomiasis control relies almost exclusively on a single drug. The neuromuscular system of schistosomes is fertile ground for therapeutic intervention, yet the details of physiological events involved in neuro...