Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains.

• Main Authors: Alberto J Leon (Author), Viktoriya Borisevich (Author), Nahal Boroumand (Author), Robert Seymour (Author), Rebecca Nusbaum (Author), Olivier Escaffre (Author), Luoling Xu (Author), David J Kelvin (Author), Barry Rockx (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide gene expression analysis of lung and brain tissues...