UBA1 inhibition contributes radiosensitization of glioblastoma cells via blocking DNA damage repair

• Main Authors: Changyong Wu (Author), Yang Shen (Author), Lin Shi (Author), Junhao Zhang (Author), Tongxuan Guo (Author), Lingni Zhou (Author), Wanzhou Wang (Author), Xu Zhang (Author), Rutong Yu (Author), Xuejiao Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is a brain tumor with high mortality and recurrence rate. Radiotherapy and chemotherapy after surgery are the main treatment options available for GBM. However, patients with glioblastoma have a grave prognosis. The major reason is that most GBM patients are resistant t...