UBA1 inhibition contributes radiosensitization of glioblastoma cells via blocking DNA damage repair

• Hoofdauteurs: Changyong Wu (Auteur), Yang Shen (Auteur), Lin Shi (Auteur), Junhao Zhang (Auteur), Tongxuan Guo (Auteur), Lingni Zhou (Auteur), Wanzhou Wang (Auteur), Xu Zhang (Auteur), Rutong Yu (Auteur), Xuejiao Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Glioblastoma multiforme (GBM) is a brain tumor with high mortality and recurrence rate. Radiotherapy and chemotherapy after surgery are the main treatment options available for GBM. However, patients with glioblastoma have a grave prognosis. The major reason is that most GBM patients are resistant t...