RNA as a feasible marker of Trypanosoma cruzi viability during the parasite interaction with the triatomine vector Rhodnius prolixus (Hemiptera, Triatominae).

• Main Authors: Paula Finamore-Araujo (Author), Gabriel Lucio Silva da Fonseca (Author), Cecília Stahl Vieira (Author), Daniele Pereira de Castro (Author), Otacilio Cruz Moreira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A recurring question concerning Trypanosoma cruzi DNA detection/quantification is related to the fact that DNA amplification, by itself, does not differentiate between viable or dead parasites. On the other hand, RNA can be considered a potential molecular marker of pathogens viability. Herein, we d...