Mechanical ventilation induces brainstem inflammation in preterm fetal sheep

• Main Authors: Kayla Vidinopoulos (Author), Zahrah Azman (Author), Ainsley Somers (Author), Valerie A. Zahra (Author), Alison Thiel (Author), Hui Lu (Author), Yen Pham (Author), Nhi Thao Tran (Author), Beth J. Allison (Author), Eric Herlenius (Author), Stuart Hooper (Author), Robert Galinsky (Author), Graeme R. Polglase (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPreterm infants have immature respiratory drive and often require prolonged periods of mechanical ventilation. Prolonged mechanical ventilation induces systemic inflammation resulting in ventilation-induced brain injury, however its effect on brainstem respiratory centers is unknown. We ai...