Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration in vivo

• Main Authors: Huiyong Liu (Author), Honglei Kang (Author), Chao Song (Author), Zuowei Lei (Author), Li Li (Author), Jianfeng Guo (Author), Yong Xu (Author), Hanfeng Guan (Author), Zhong Fang (Author), Feng Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Low back pain (LBP) is a common worldwide disease that causes an enormous social economic burden. Intervertebral disc degeneration (IDD) is considered as a major cause of LBP. The process of IDD is complicated and involves both inflammation and senescence. The production of pro-inflammatory cytokine...