Cell-Culture-Dependent Change of Ca2+ Response of Rat Aortic Myocytes to Sphingosine-1-Phosphate

• Main Authors: Ryoichi Tanaka (Author), Katsuhiko Muraki (Author), Susumu Ohya (Author), Yuka Itoh (Author), Noriyuki Hatano (Author), Yuji Imaizumi (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We characterized the effects of sphingosine-1-phosphate (S1P) on rat aortic myocytes with or without culture. Application of S1P induced a small Ca2+ response in 40% freshly dispersed aortic myocytes, whereas S1P caused a larger Ca2+ response in 90% myocytes cultured for 72 h. Concentration-response...