Luminal Fluid Motion Inside an In Vitro Dissolution Model of the Human Ascending Colon Assessed Using Magnetic Resonance Imaging

• Main Authors: Connor O'Farrell (Author), Caroline L. Hoad (Author), Konstantinos Stamatopoulos (Author), Luca Marciani (Author), Sarah Sulaiman (Author), Mark J. H. Simmons (Author), Hannah K. Batchelor (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Knowledge of luminal flow inside the human colon remains elusive, despite its importance for the design of new colon-targeted drug delivery systems and physiologically relevant in silico models of dissolution mechanics within the colon. This study uses magnetic resonance imaging (MRI) techniques to...