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RIG-I Signaling via MAVS Is Dispensable for Survival in Lethal Influenza Infection In Vivo

Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines. It requires interaction with an adaptor molecule, mitochondrial antiviral-signaling protein (MAVS), to activate downstream signaling pathways. To elucidate th...

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Main Authors: Wenxin Wu (Author), Xiaoqiu Wang (Author), Wei Zhang (Author), Lili Tian (Author), J. Leland Booth (Author), Elizabeth S. Duggan (Author), Sunil More (Author), Lin Liu (Author), Mikhail Dozmorov (Author), Jordan P. Metcalf (Author)
Format: Book
Published: Hindawi Limited, 2018-01-01T00:00:00Z.
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