Sulphonylurea usage in melioidosis is associated with severe disease and suppressed immune response.

• Main Authors: Xiang Liu (Author), Geraldine Foo (Author), Wan Peng Lim (Author), Sharada Ravikumar (Author), Siew Hoon Sim (Author), Mar Soe Win (Author), Jessamine Geraldine Goh (Author), Joan Hui Juan Lim (Author), Ying Hui Ng (Author), Dale Fisher (Author), Chin Meng Khoo (Author), Gladys Tan (Author), Louis Yi Ann Chai (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Melioidosis is a problem in the developing tropical regions of Southeast Asia and Northern Australia where the the Gram negative saprophytic bacillus Burkholderia pseudomallei is endemic with the risk of fulminant septicaemia. While diabetes mellitus is a well-established risk factor for...