Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia

• Egile Nagusiak: Sara Chiappalupi (Egilea), Guglielmo Sorci (Egilea), Aleksandra Vukasinovic (Egilea), Laura Salvadori (Egilea), Roberta Sagheddu (Egilea), Dario Coletti (Egilea), Giorgia Renga (Egilea), Luigina Romani (Egilea), Rosario Donato (Egilea), Francesca Riuzzi (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2020-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer‐associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy caused by systemic inflammation is a...