Cholesterol Dysmetabolism in Alzheimer's Disease: A Starring Role for Astrocytes?

• Main Authors: Erica Staurenghi (Author), Serena Giannelli (Author), Gabriella Testa (Author), Barbara Sottero (Author), Gabriella Leonarduzzi (Author), Paola Gamba (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent decades, the impairment of cholesterol metabolism in the pathogenesis of Alzheimer's disease (AD) has been intensively investigated, and it has been recognized to affect amyloid β (Aβ) production and clearance, tau phosphorylation, neuroinflammation and degeneration. In particular, th...