The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways

• Main Authors: Karema Abu-Elfotuh (Author), Heba Mohammed Refat M. Selim (Author), Omnia Karem M. Riad (Author), Ahmed M. E. Hamdan (Author), Soha Osama Hassanin (Author), Asmaa F. Sharif (Author), Nouran Magdy Moustafa (Author), Ayah M.H. Gowifel (Author), Marwa Y. A. Mohamed (Author), Ahmed M. Atwa (Author), Sameh S. Zaghlool (Author), Mahmoud Nour El-Din (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Aluminium (Al) is accumulated in the brain causing neurotoxicity and neurodegenerative disease like Alzheimer's disease (AD), multiple sclerosis, autism and epilepsy. Hence, attenuation of Al-induced neurotoxicity has become a "hot topic" in looking for an intervention t...