Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.

• Główni autorzy: James A Thomas (Autor), Nicola Baker (Autor), Sebastian Hutchinson (Autor), Caia Dominicus (Autor), Anna Trenaman (Autor), Lucy Glover (Autor), Sam Alsford (Autor), David Horn (Autor)
• Format: Książka
• Wydane: Public Library of Science (PLoS), 2018-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Chemotherapy continues to have a major impact on reducing the burden of disease caused by trypanosomatids. Unfortunately though, the mode-of-action (MoA) of antitrypanosomal drugs typically remains unclear or only partially characterised. This is the case for four of five current drugs used to treat...