Exogenous CFH Modulates Levels of Pro-Inflammatory Mediators to Prevent Oxidative Damage of Retinal Pigment Epithelial Cells with the At-Risk CFH Y402H Variant

• 主要な著者: Henry Velazquez-Soto (著者), Sergio Groman-Lupa (著者), Marisa Cruz-Aguilar (著者), Alberto L. Salazar (著者), Juan C. Zenteno (著者), Maria C. Jimenez-Martinez (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Age-related macular degeneration (AMD) is a complex, progressive degenerative retinal disease. Retinal pigment epithelial (RPE) cells play an important role in the immune defense of the eye and their dysfunction leads to the progressive irreversible degeneration of photoreceptors. Genetic factors, c...