Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells

• Main Authors: Soma Noguchi (Author), Taketoshi Kajimoto (Author), Takuya Kumamoto (Author), Masashi Shingai (Author), Soshi Narasaki (Author), Tomoaki Urabe (Author), Serika Imamura (Author), Kana Harada (Author), Izumi Hide (Author), Sigeru Tanaka (Author), Yuhki Yanase (Author), Shun-Ichi Nakamura (Author), Yasuo M. Tsutsumi (Author), Norio Sakai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: In this study, we aimed to elucidate the action mechanisms of propofol, particularly those underlying propofol-induced protein kinase C (PKC) translocation.Experimental approach: Various PKCs fused with green fluorescent protein (PKC-GFP) or other GFP-fused proteins were expr...