The Single Dose Poloxamer 407 Model of Hyperlipidemia; Systemic Effects on Lipids Assessed Using Pharmacokinetic Methods, and its Effects on Adipokines

Purpose: The induction of hyperlipidemia using poloxamer 407 (P407) is gaining use for studying the effect of the condition on drug pharmacokinetics. Although a single intraperitoneal dose of P407 causes a rapid onset of hyperlipidemia, the initial lipid concentrations are much higher than seen in h...

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Bibliographic Details
Main Authors: Hetal R Chaudhary (Author), Dion R Brocks (Author)
Format: Book
Published: Frontiers Media S.A., 2013-02-01T00:00:00Z.
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3rd Floor Main Library

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