Mismatch repair deficiency in early‐onset duodenal, ampullary, and pancreatic carcinomas is a strong indicator for a hereditary defect

• Главные авторы: Valentyna Kryklyva (Автор), Lodewijk AA Brosens (Автор), Monica AJ Marijnissen‐van Zanten (Автор), Marjolijn JL Ligtenberg (Автор), Iris D Nagtegaal (Автор)
• Формат: ‌
• Опубликовано: Wiley, 2022-03-01T00:00:00Z.
• Предметы: article
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Abstract Mismatch repair deficiency (dMMR) is a hallmark of Lynch syndrome (LS), but its prevalence in early‐onset (diagnosed under the age of 50 years) duodenal, ampullary, and pancreatic carcinomas (DC, AC, and PC, respectively) is largely unknown. We explored the prevalence of dMMR and the underl...