Hydrogel Delivery Device for the In Vitro and In Vivo Sustained Release of Active rhGALNS Enzyme

• Main Authors: Michael Flanagan (Author), Qi Gan (Author), Saahil Sheth (Author), Rachel Schafer (Author), Samuel Ruesing (Author), Linda E. Winter (Author), Karoly Toth (Author), Silviya P. Zustiak (Author), Adriana M. Montaño (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2023-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Morquio A disease is a genetic disorder resulting in N-acetylgalactosamine-6-sulfate sulfatase (GALNS) deficiency, and patients are currently treated with enzyme replacement therapy via weekly intravenous enzyme infusions. A means of sustained enzyme delivery could improve patient quality of life by...