Matrix Metalloproteinase-9-Dependent Release of IL-1β by Human Eosinophils

• Main Authors: Stephane Esnault (Author), Elizabeth A. Kelly (Author), Sean H. Johnson (Author), Larissa P. DeLain (Author), Madeline J. Haedt (Author), Andrea L. Noll (Author), Nathan Sandbo (Author), Nizar N. Jarjour (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Asthma is often associated with airway eosinophilia, and therapies targeting eosinophils are now available to treat severe eosinophilic asthma. Eosinophilic asthma is often due to a type-2 immune response and production of IL-5, which leads to eosinophilopiesis and recruitment of mature eosinophils...