Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD

• Autores principales: Mingyao Sun (Autor), Nicole Hines (Autor), Diego Scerbo (Autor), Jane Buchanan (Autor), Chaorong Wu (Autor), Patrick Ten Eyck (Autor), Diana Zepeda-Orozco (Autor), Eric B. Taylor (Autor), Diana I. Jalal (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2022-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Xanthine oxidase (XO) contributes to oxidative stress and vascular disease. Hyperuricemia and gout are common in patients with chronic kidney disease (CKD), a population at increased risk of vascular disease. We evaluated effects of allopurinol on serum XO activity and metabolome of CKD patients who...