Improved therapeutic index of an acidic pH-selective antibody

Although therapeutically efficacious, ipilimumab can exhibit dose-limiting toxicity that prevents maximal efficacious clinical outcomes and can lead to discontinuation of treatment. We hypothesized that an acidic pH-selective ipilimumab (pH Ipi), which preferentially and reversibly targets the acidi...

Full description

Saved in:
Bibliographic Details
Main Authors: Peter S. Lee (Author), Katherine G. MacDonald (Author), Evan Massi (Author), Pamela V. Chew (Author), Christine Bee (Author), Padma Perkins (Author), Bryant Chau (Author), Kent Thudium (Author), Jack Lohre (Author), Pradyot Nandi (Author), Ekaterina G. Deyanova (Author), Ishita Barman (Author), Olafur Gudmundsson (Author), Gavin Dollinger (Author), Tim Sproul (Author), John J. Engelhardt (Author), Pavel Strop (Author), Arvind Rajpal (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available