Improved therapeutic index of an acidic pH-selective antibody
Although therapeutically efficacious, ipilimumab can exhibit dose-limiting toxicity that prevents maximal efficacious clinical outcomes and can lead to discontinuation of treatment. We hypothesized that an acidic pH-selective ipilimumab (pH Ipi), which preferentially and reversibly targets the acidi...
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Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Libro |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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Acceso en línea: | Connect to this object online. |
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Internet
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Número de Clasificación: |
A1234.567 |
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Copia 1 | Disponible |