Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring

• Main Authors: Rizzardi Anthony E (Author), Johnson Arthur T (Author), Vogel Rachel (Author), Pambuccian Stefan E (Author), Henriksen Jonathan (Author), Skubitz Amy PN (Author), Metzger Gregory J (Author), Schmechel Stephen C (Author)
• Format: Book
• Published: BMC, 2012-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Immunohistochemical (IHC) assays performed on formalin-fixed paraffin-embedded (FFPE) tissue sections traditionally have been semi-quantified by pathologist visual scoring of staining. IHC is useful for validating biomarkers discovered through genomics methods as...