Temporal Clinical and Laboratory Response to Interleukin-6 Receptor Blockade With Tocilizumab in 89 Hospitalized Patients With COVID-19 Pneumonia

• Main Authors: Daria Fomina (Author), Mar'yana A. Lysenko (Author), Irina P. Beloglazova (Author), Zinaida Yu. Mutovina (Author), Nataliya G. Poteshkina (Author), Inna V. Samsonova (Author), Tat'yana S. Kruglova (Author), Anton A. Chernov (Author), Alexander V. Karaulov (Author)
• Format: Book
• Published: Case Western Reserve University, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pandemic COVID-19 pneumonia due to SARS-2 is an important cause of morbidity and mortality. Emerging evidence links poor outcomes to an inflammatory cytokine storm. Methods: We treated 89 hospitalized patients with COVID-19 pneumonia and heightened systemic inflammation (elevated serum C...