Development of a drug delivering round window niche implant for cochlear pharmacotherapy

• Main Authors: Chunjiang Wei (Author), Ziwen Gao (Author), Martina Knabel (Author), Martin Ulbricht (Author), Stefan Senekowitsch (Author), Peter Erfurt (Author), Norman Maggi (Author), Bastian Zwick (Author), Thomas Eickner (Author), Farnaz Matin-Mann (Author), Anne Seidlitz (Author), Thomas Lenarz (Author), Verena Scheper (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background There exists an unfulfilled requirement for effective cochlear pharmacotherapy. Controlled local drug delivery could lead to effective bioavailability. The round window niche (RWN), a cavity in the middle ear, is connected to the cochlea via a membrane through which drug can diffuse. We a...