Combined using of paclitaxel and salinomycin active targeting nanostructured lipid carriers against non-small cell lung cancer and cancer stem cells

• Main Authors: Jianwen Zhou (Author), Mingshuang Sun (Author), Shanshan Jin (Author), Li Fan (Author), Wenquan Zhu (Author), Xiaoyu Sui (Author), Lixin Cao (Author), Chunrong Yang (Author), Cuiyan Han (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The existing of avidity cancer stem cells (CSCs) made it an optical strategy to kill cancer cells and CSCs at the same time. Here, we constructed a CSCs specific nanocarrier naming T-S-NLC using the CD133+ targeting peptide TISWPPR (TR) as the targeting moiety attached to the distal end of PEG on sa...