The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice

• Main Authors: Francisco J. Bermudez-Silva (Author), Silvana Y. Romero-Zerbo (Author), Magalie Haissaguerre (Author), Inmaculada Ruz-Maldonado (Author), Said Lhamyani (Author), Rajaa El Bekay (Author), Antoine Tabarin (Author), Giovanni Marsicano (Author), Daniela Cota (Author)
• Format: Book
• Published: The Company of Biologists, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The endocannabinoid system (ECS) is an intercellular signalling mechanism that is present in the islets of Langerhans and plays a role in the modulation of insulin secretion and expansion of the β-cell mass. The downstream signalling pathways mediating these effects are poorly understood. Mammalian...