The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice

• Hauptverfasser: Francisco J. Bermudez-Silva (Verfasst von), Silvana Y. Romero-Zerbo (Verfasst von), Magalie Haissaguerre (Verfasst von), Inmaculada Ruz-Maldonado (Verfasst von), Said Lhamyani (Verfasst von), Rajaa El Bekay (Verfasst von), Antoine Tabarin (Verfasst von), Giovanni Marsicano (Verfasst von), Daniela Cota (Verfasst von)
• Format: Buch
• Veröffentlicht: The Company of Biologists, 2016-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The endocannabinoid system (ECS) is an intercellular signalling mechanism that is present in the islets of Langerhans and plays a role in the modulation of insulin secretion and expansion of the β-cell mass. The downstream signalling pathways mediating these effects are poorly understood. Mammalian...