M2 polarization enhances silica nanoparticle uptake by macrophages

While silica nanoparticles have enabled numerous industrial and medical applications, their toxicological safety requires further evaluation. Macrophages are the major cell population responsible for nanoparticle clearance in vivo. The prevailing macrophage phenotype largely depends on the local imm...

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Main Authors: Jessica eHoppstädter (Author), Michelle eSeif (Author), Anna eDembek (Author), Christian eCavelius (Author), Hanno eHuwer (Author), Annette eKraegeloh (Author), Alexandra K Kiemer (Author)
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Publicado em: Frontiers Media S.A., 2015-03-01T00:00:00Z.
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