Administration of mRNA-Nanomedicine-Augmented Calvarial Defect Healing via Endochondral Ossification

• Main Authors: Hsi-Kai Tsou (Author), Cheng-Hsin Wu (Author), Long Yi Chan (Author), Kazunori Kataoka (Author), Nanae Itokazu (Author), Minoru Tsuzuki (Author), Hsuan Hu (Author), Guan-Yu Zhuo (Author), Keiji Itaka (Author), Chin-Yu Lin (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Large-area craniofacial defects remain a challenge for orthopaedists, hastening the need to develop a facile and safe tissue engineering strategy; osteoconductive material and a combination of optimal growth factors and microenvironment should be considered. Faced with the unmet need, we propose tha...