Characterization of Pneumococcal Colonization Dynamics and Antimicrobial Resistance Using Shotgun Metagenomic Sequencing in Intensively Sampled South African Infants

• Main Authors: Rendani I. Manenzhe (Author), Felix S. Dube (Author), Meredith Wright (Author), Katie Lennard (Author), Stephanie Mounaud (Author), Stephanie W. Lo (Author), Heather J. Zar (Author), William C. Nierman (Author), Mark P. Nicol (Author), Clinton Moodley (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: There remains a significant proportion of deaths due to pneumococcal pneumonia in infants from low- and middle-income countries despite the marginal global declines recorded in the past decade. Monitoring changes in pneumococcal carriage is key to understanding vaccination-induced shifts...