Emerging roles of Aurora-A kinase in cancer therapy resistance

• Main Authors: Dayong Zheng (Author), Jun Li (Author), Han Yan (Author), Gang Zhang (Author), Wei Li (Author), Edward Chu (Author), Ning Wei (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aurora kinase A (Aurora-A), a serine/threonine kinase, plays a pivotal role in various cellular processes, including mitotic entry, centrosome maturation and spindle formation. Overexpression or gene-amplification/mutation of Aurora-A kinase occurs in different types of cancer, including lung cancer...