Pharmacokinetic and pharmacodynamic drug-drug interactions between evogliptin and empagliflozin or dapagliflozin in healthy male volunteers

• Main Authors: Dasohm Kim (Author), Minkyu Choi (Author), Byung Hak Jin (Author), Taegon Hong (Author), Choon Ok Kim (Author), Byung Won Yoo (Author), Min Soo Park (Author)
• Format: Knjiga
• Izdano: Wiley, 2023-08-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Evogliptin (EV) is a novel dipeptidyl peptidase‐4 inhibitor (DPP4i) for glycemic control in patients with type 2 diabetes mellitus (T2DM). This study evaluated the pharmacokinetic (PK) and pharmacodynamic (PD) interactions between EV and sodium glucose cotransporter‐2 inhibitors (SGLT2i) in...