Characterization of Primary Cilia Formation in Human ESC-Derived Retinal Organoids

• Main Authors: Ke Ning (Author), Ziming Luo (Author), Tia J. Kowal (Author), Matthew Tran (Author), Rishab Majumder (Author), Trent M. Jarin (Author), Albert Y. Wu (Author), Jeffrey L. Goldberg (Author), Yang Sun (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives. Primary cilia are conserved organelles found in polarized mammalian cells that regulate neuronal growth, migration, and differentiation. Proper cilia formation is essential during eye development. Our previous reports found that both amacrine and retinal ganglion cells (RGCs) contain pri...