A pipeline for identifying guide RNA sequences that promote RNA editing of nonsense mutations that cause inherited retinal diseases
Adenosine deaminases acting on RNA (ADARs) are endogenous enzymes catalyzing the deamination of adenosines to inosines, which are then read as guanosines during translation. This ability to recode makes ADAR an attractive therapeutic tool to edit genetic mutations and reprogram genetic information a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2024-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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