Plasma leptin concentrations are greater in type II diabetic patients and stimulate monocyte chemotactic peptide-1 synthesis via the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway

• Main Authors: Jin Joo Cha (Author), Young Youl Hyun (Author), Yi Hwa Jee (Author), Mi Jin Lee (Author), Kum Hyun Han (Author), Young Sun Kang (Author), Sang Youb Han (Author), Dae Ryong Cha (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Leptin is an adipokine that is recently reported to be a biomarker of systemic inflammation. Although atherosclerosis causes cardiovascular diseases, it is not clear whether leptin contributes to the acceleration of this process. In this study, we investigated whether alterations of plas...