Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway

• Główni autorzy: Wen-qiang Cao (Autor), Xiao-qian Zhai (Autor), Ji-wei Ma (Autor), Xue-qi Fu (Autor), Bai-song Zhao (Autor), Pu Zhang (Autor), Xiao-yan Fu (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Context Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle. Objective To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism. Materials and met...