Analysis of the interactome of Schistosoma mansoni histone deacetylase 8.

• Main Authors: Stéphanie Caby (Author), Lucile Pagliazzo (Author), Julien Lancelot (Author), Jean-Michel Saliou (Author), Nicolas Bertheaume (Author), Raymond J Pierce (Author), Emmanuel Roger (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone deacetylase 8 from Schistosoma mansoni (SmHDAC8) is essential to parasite growth and development within the mammalian host and is under investigation as a target for the development of selective inhibitors as novel schistosomicidal drugs. Although some protein substrates and protein partners...