MicroRNA-145 Increases the Apoptosis of Activated Hepatic Stellate Cells Induced by TRAIL through NF-κB Signaling Pathway

• Main Authors: Junfa Yang (Author), Qingxue Liu (Author), Shiyang Cao (Author), Tao Xu (Author), Xiaofeng Li (Author), Dandan Zhou (Author), Linxin Pan (Author), Changyao Li (Author), Cheng Huang (Author), Xiaoming Meng (Author), Lei Zhang (Author), Xiao Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During the liver fibrosis recovery stage tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can effectively induce apoptosis of activated hepatic stellate cells (HSCs). Normal hepatic stellate cells are resistant to TRAIL cytotoxicity. Therefore, enhancing the sensitivity of TRAIL-induc...