Coptidis Rhizoma Suppresses Metastatic Behavior by Inhibiting TGF-β-Mediated Epithelial-Mesenchymal Transition in 5-FU-Resistant HCT116 Cells

• Main Authors: Yong-Hwi Kang (Author), Jing-Hua Wang (Author), Jin-Seok Lee (Author), Nam-Hun Lee (Author), Chang-Gue Son (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Colorectal cancer (CRC) is the second most lethal malignancy worldwide. The high mortality rate of CRC is largely due to cancer metastasis. Recently, suppressing epithelial-to-mesenchymal transition (EMT) has been considered a promising strategy for treating metastatic cancer, especially drug-resist...