The Fate of Sialic Acid and PEG Modified Epirubicin Liposomes in Aged versus Young Cells and Tumor Mice Models

• Main Authors: Dezhi Sui (Author), Xianmin Meng (Author), Changzhi Li (Author), Xueying Tang (Author), Ying Qin (Author), Ning Zhang (Author), Junqiang Ding (Author), Xinrong Liu (Author), Yihui Deng (Author), Yanzhi Song (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In preclinical studies of young mice, nanoparticles showed excellent anti-tumor therapeutic effects by harnessing Peripheral Blood Monocytes (PBMs) and evading the immune system. However, the changes of age will inevitably affect PBMs and the immune system, and there is a serious lack of relevant re...