Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans.

• Main Authors: Katharina Röltgen (Author), Kobina Assan-Ampah (Author), Emelia Danso (Author), Dorothy Yeboah-Manu (Author), Gerd Pluschke (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium ulcerans (M. ulcerans), the causative agent of the devastating skin disease Buruli ulcer (BU), is characterized by an extremely low level of genetic diversity. Recently, we have reported the first discrimination of closely related M. ulcerans variants in the BU endemic Densu River Vall...