A Carbazole Derivative Protects Cells Against Endoplasmic Reticulum (ER) Stress and Glutathione Depletion

• Main Authors: Hikari Miura (Author), Katsura Takano (Author), Yasuko Kitao (Author), Satoshi Hibino (Author), Tominari Choshi (Author), Rika Murakami (Author), Hiroto Suzuki (Author), Masashi Yamada (Author), Satoshi Ogawa (Author), Osamu Hori (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enhanced levels of intracellular stresses such as oxidative stress and endoplasmic reticulum (ER) stress are implicated in various neuropathological conditions including brain ischemia and neurodegeneration. During a search for compounds that regulate ER stress and ER stress-induced cell death, we i...