Merging Experimental Design and Nanotechnology for the Development of Optimized Simvastatin Spanlastics: A Promising Combined Strategy for Augmenting the Suppression of Various Human Cancer Cells

• Main Authors: Shaimaa M. Badr-Eldin (Author), Hibah M. Aldawsari (Author), Nabil A. Alhakamy (Author), Usama A. Fahmy (Author), Osama A. A. Ahmed (Author), Thikryat Neamatallah (Author), Singkome Tima (Author), Raghad H. Almaghrabi (Author), Fayda M. Alkudsi (Author), Asmaa A. Alamoudi (Author), Amjad A. Alzahrani (Author), Sabna Kotta (Author), Omar D. Al-hejaili (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Simvastatin (SMV) is an antihyperlipidemic agent that has been investigated as a possible anti-cancer agent. An obstacle to malignant tumor therapy using drugs is the delivery of adequate levels to the cancer cells while minimizing side effects following their systemic administration. To circumvent...