Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury

• Những tác giả chính: Juanjuan Lu (Tác giả), Jie Wang (Tác giả), Long Yu (Tác giả), Rong Cui (Tác giả), Ying Zhang (Tác giả), Hanqing Ding (Tác giả), Guofeng Yan (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2022-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Microglia in the penumbra shifted from M2 to M1 phenotype between 3 and 5 days after cerebral ischemia-reperfusion, which promoted local inflammation and injury. Shaoyao-Gancao Decoction (SGD) has been found to result in a significant upregulation of IL-13 in the penumbra, which has been shown to in...