Synthesis and Biological Evaluation of (<i>S</i>)-2-(Substituted arylmethyl)-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-<i>a</i>]indole-3-carboxamide Analogs and Their Synergistic Effect against PTEN-Deficient MDA-MB-468 Cells

A series of twenty-six compounds of furfuryl or benzyl tetrahydropyrazino[1,2-<i>a</i>]indole analogs were synthesized and evaluated for cytotoxic activity against the estrogen receptor (ER)-positive breast cancer cell line (MCF-7) and the epidermal growth factor receptor (EGFR) over-exp...

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Main Authors: Ye-Mi Kwon (Author), Sou Hyun Kim (Author), Young-Suk Jung (Author), Jae-Hwan Kwak (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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