Synthesis and Biological Evaluation of (<i>S</i>)-2-(Substituted arylmethyl)-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-<i>a</i>]indole-3-carboxamide Analogs and Their Synergistic Effect against PTEN-Deficient MDA-MB-468 Cells

• Үндсэн зохиолчид: Ye-Mi Kwon (Зохиогч), Sou Hyun Kim (Зохиогч), Young-Suk Jung (Зохиогч), Jae-Hwan Kwak (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

A series of twenty-six compounds of furfuryl or benzyl tetrahydropyrazino[1,2-<i>a</i>]indole analogs were synthesized and evaluated for cytotoxic activity against the estrogen receptor (ER)-positive breast cancer cell line (MCF-7) and the epidermal growth factor receptor (EGFR) over-exp...